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Genetics

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Analysis of Genes and Genomes

Hartl Daniel

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Edición 7
Editorial Jones and Bartlett Publishers
Fecha publicación 2009
Formato Tapa Dura
Páginas 763
ISBN 076375868X
ISBN13 9780763758684
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Medicina >> Genética

 

Written by two renowned authorities, Genetics: Analysis of Genes and Genomes, Seventh Edition provides the most current, clear, comprehensive and balanced introduction to genetics and genomics at the college level. Expanding upon the key elements that have made the text a success, the authors have added important new material to virtually every chapter, including sections on High-throughput genotyping, massively parallel sequencing, comparative genomics, genomic islands, copy number polymorphisms, characteristics of  Quantitative Trait Loci for disease risk factors, and much more.  They continue to treat transmission genetics, molecular genetics, and evolutionary genetics as fully integrated subjects and provide students with an unprecedented understanding of the basic process of gene transmission, mutation, expression and regulation.  Integrated critical thinking exercises and problem sets allow for a mastery of key genetic concepts, while the end-of-chapter Guide to Problem-Solving sections demonstrate the concepts needed to efficiently solve problems and understand the reasoning behind the correct answer.


Daniel L. Hartl, PhD, Harvard University

1 Introduction to molecular genetics and genomics 1
2 DNA structure and DNA manipulation 42
3 Transmission genetics : the principle of segregation 88
4 Chromosomes and sex-chromosome inheritance 134
5 Genetic linkage and chromosome mapping 176
6 Molecular biology of DNA replication and recombination 222
7 Molecular organization of chromosomes 260
8 Human karyotypes and chromosome behavior 294
9 Genetics of bacteria and their viruses 344
10 Molecular biology of gene expression 398
11 Molecular mechanisms of gene regulation 444
12 Genomics, proteomics, and transgenics 500
13 Genetic control of development 550
14 Molecular mechanisms of mutation and DNA repair 592
15 Molecular genetics of the cell cycle and cancer 642
16 Mitochondrial DNA and extranuclear inheritance 686
17 Molecular evolution and population genetics 716
18 The genetic basis of complex inheritance 760



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