Now completely revised and updated, this ground-breaking text focuses on the borderland between histology and pathology. The text describes human histology and its variations, with emphasis on avoiding overdiagnosis or misdiagnosis of normal variants. Presented by leading international specialists in pathology, histopathology, anatomical pathology, surgical pathology, and neuropathology, the text is innovative, well organized and generously illustrated. Coverage includes the structure, composition, and function of tissues from a pathologic perspective; a systematic review of each major organ system, as well as structures of special significance; and histologic subtleties, such as unusual variations in staining reactions, little-known fixation artifacts, and frequently missed gross observations.

This edition is reorganized to better reflect an organ-system approach to histology. Immunohistochemical findings in normal tissues have been added, based on the latest antibody panels.

A bound-in CD-ROM image bank is included.

CUTANEOUS TISSUE

Normal Skin
Min Li and Carlos D. Urmacher

Nail
Julian Conejo-Mir and Luis Requena

BREAST

Breast
Laura Collins and Stuart J. Schnitt

SKELETAL SYSTEM

Bone
Sanford I. Roth and Andrew Rosenberg

Joints
Peter G. Bullough

SOFT TISSUES

Myofibroblast
Walter Schürch, Thomas A. Seemayer, Boris Hinz, and Giulio Gabbiani

Adipose Tissue
John S. J. Brooks and Patricia M. Perosio

Skeletal Muscle
Reid R. Heffner, Jr. and Lucia L. Balos

Peripheral Nervous System
Carlos Ortiz-Hidalgo and Roy O. Weller

Blood Vessels
Patrick J. Gallagher

CENTRAL NERVOUS SYSTEM

Central Nervous System
Gregory N. Fuller and Peter Burger

Pituitary and Sellar Region
M. Beatriz S. Lopes, Peter J. Pernicone, Bernd W. Scheithauer, Eva Horvath, and Kalman Kovacs

HEAD AND NECK

Normal Eye and Ocular Adnexa
Gordon K. Klintworth and Thomas J. Cummings

Ear
Bruce M. Wenig

Mouth, Nose, and Paranasal Sinuses
Karoly Balogh and Liron Pantanowitz

Larynx and Pharynx
Stacey E. Mills

Major Salivary Glands
Fernando Martínez-Madrigal, Jaques Bosq, and Odile Casiraghi

THORAX AND SEROUS MEMBRANES

Lungs
Thomas V. Colby, Kevin O. Leslie, and Samuel A. Yousem

Thymus
Saul Suster and Juan Rosai

Heart
Gerald Berry and Margaret E. Billingham

Serous Membranes
Darryl Carter, Lawrence True, and Christopher N. Otis

ALIMENTARY TRACT

Esophagus
Franco G. DeNardi andRobert Riddell

Stomach
David A. Owen

Small Intestine
Terry L. Gramlich and Robert E. Petras

Colon
Julia Dahl and Joel K. Greenson

Vermiform Appendix
Terry L. Gramlich and Robert E. Petras

Anal Canal
Claus Fenger

Liver
Arief A. Suriawinata and Swan N. Thung

Gallbladder and Extrahepatic Biliary System
Edward B. Stelow, Seung-Mo Hung, and Henry F. Frierson, Jr.

Pancreas
David S. Klimstra

HEMATOPOIETIC SYSTEM

Lymph Nodes
Paul van der Valk and Chris J.L.M. Meijer

Spleen
J. Han. J. M. van Krieken and Attilio Orazi

Bone Marrow
S. N. Wickramasinghe

GENITOURINARY TRACT

Kidney
William L. Clapp and Byron P. Croker

Bladder, Ureter, and Pelvis
Victor E. Reuter

Prostate
John E. McNeal

Testis and Excretory Duct System
Thomas D. Trainer

Penis and Distal Urethra
Elsa F. Velazquez, Christopher J. Cold, José E. Barreto, and Antonio L. Cubilla

FEMALE GENITAL TRACT

Vulva
Edward J. Wilkinson and Nancy S. Hardt

Vagina
Stanley J. Robboy and Rex C. Bentley

Uterus and Fallopian Tubes
Michael R. Hendrickson, Richard L. Kempson, and Kristen Atkins

Ovary
Philip B. Clement

Placenta
Steven H. Lewis and Kurt Benirschke

ENDOCRINE

Thyroid
Maria Luisa Carcangiu

Parathyroid
Sanford I. Roth, Nicole A. Belsley, and Graziella M. Abu-Jawdeh

Adrenal
J. Aidan Carney and Ricardo V. Lloyd

Neuroendocrine
Ronald A. DeLellis and Yogeshwar Dayal

Paraganglia
Arthur S. Tischler