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Bacterial Resistance to Antimicrobials

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Edición 2
Editorial CRC Press Inc.
Fecha publicación 2008
Formato Tapa Dura
Páginas 448
ISBN 0849391903
ISBN13 9780849391903
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Medicina >> Farmacología y Toxicologi­a
Medicina >> Infectologí­a y Enfermedades Infecciosas
Medicina >> Microbiologi­a

 

This book encompasses a broad range of concepts relating to the evolution, acquisition, development, and detection of antimicrobial resistance. There is a unique focus on the nature of antimicrobial resistance from multiple perspectives that emphasize the influence of the environment on the ecology of genes and phenotypic characteristics.


Foreword

Preface

Contributors

A Historical Introduction
1 The Ecology of Antibiotic Resistance Genes 1
2 Antibiotic Resistance: How Bacterial Populations Respond to a Simple Evolutionary Force 19
3 Global Response Systems That Cause Resistance 37
4 Drug Efflux 61
5 Mechanisms of Aminoglycoside Antibiotic Resistance 91
6 [beta]-Lactamases and Resistance to [beta]-Lactam Antibiotics 123
7 Target Modification as a Mechanisms of Antimicrobial Resistance 161
8 Antibiotic Permeability 193
9 Phenotypic Tolerance of Bacteria 209
10 Resistance as a Worldwide Problem 223
11 Genetic Methods for Detecting Bacterial Resistance Genes 239
12 Evolution and Epidemiology of Antibiotic-Resistant Pneumococci 265
13 Resistance Problems Associated with the Enterococcus 295
14 Methicillin Resistance in Staphylococcus aureus 331
15 Drug Resistance and Tuberculosis Chemotherapy - From Concept to Genomics 355
16 Antibiotic Resistance in Enterobacteria 405
17 Public Health Responses to Antimicrobial Resistance in Outpatient and Inpatient Settings 427
18 Approaches to New Antimicrobial Targets in the Age of Genomics 455

Index 479



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