Contributors viii

Preface x

1 Microbial Perspectives in the Twenty-First Century William Wade 3

2 Diagnosis, Epidemiology, and Global Impact of Endodontic Infections Dag &Ophi;rstavik 12

3 Microbiology of Caries and Dentinal Tubule Infection Robert M. Love 22

4 Culture-Based Analysis of Endodontic Infections Gunnar Dahlén 40

5 Molecular Analysis of Endodontic Infections José F. Siqueira, Jr Isabela N. R&ohat;&ccidle;as 68

6 Extraradicular Endodontic Infections Leif Tronstad 108

7 Virulence of Endodontic Bacterial Pathogens Christine M. Sedgley 130

8 Herpesviruses in Endodontic Pathosis Mohammad Sabeti 152

9 Fungi in Endodontic Infections Bilge Hakan Sen B. G&uddot;niz Baksi 164

10 Management of Aggressive Head and Neck Infections Domenick P. Colletti Robert A. Ord 195

11 Endodontic Infections and Pain Anibal Diogenes Ken M. Hargreaves 213

12 Systemic Antibiotics in Endodontic Infections J. Craig Baumgartner John R. Smith 225

13 Topical Antimicrobials in Endodontic Therapy Tuomas Waltimo Matthias Zehnder 242

14 Endodontic Infections in Incompletely Developed Teeth George T. -J. Huang 261

15 Prognosis in the Treatment of Teeth with Endodontic Infections Shimon Friedman 281

16 Endodontic Infections and Systemic Disease Ashraf F. Fouad 320

Glossary 339

Index 343