This book provides a definitive reference work on the developing brain, from conception through the first year of life. Its purpose is to provide the range of specialists involved in the management of the fetus and the neonate with the latest information on the developmental neurology and pathology of the developing central nervous system, so that they can provide prompt and informed treatment of neurological disability — the most feared complication of pregnancy and the early months of the life of the newborn child.
A cross-specialty book: brings together the work of specialists on the immature brain from the fields of obstetrics, paediatrics and neurosurgery.
An international book: edited and written by an international team of experts.
Highly illustrated: includes over 800 images and line drawings that capture the latest investigative techniques.
Focused on treatment: key points boxes pick out the most important information for the busy specialist.
Evidence-based information: extensively referenced with the latest and most important papers and articles.
Includes the latest ultrasound techniques — to reflect the massive improvements since the last edition.
Medico-legal issues highlighted — in recognition of the role of specialists as expert witnesses.
Covers the latest MR techniques: fast sequences for fetal brain imaging, DWI, tractography.
SECTION I Structural Development of the CNS
1. Genetic and Epigenetic Control of the Early Brain Development
2. Early Embryonic and Fetal Development
3. The Emergence of Consciousness
4. Ultrasound Assessment of Normal Fetal Brain Development
5. MR Imaging of the Fetal Brain
6. Imaging the Neonatal Brain
7. Insights Using New MR Techniques
SECTION II Functional Assessment of CNS Development
8. Functional Assessment of the Fetal CNS
9. The Fetal Senses
10. Clinical Assessment of the Infant Nervous System
11. Doppler Assessment of the Fetal and Neonatal Brain
12. Measurement of CBF and Metabolism of the Developing Brain
13. Neonatal Neurophysiology
SECTION III Anomalies
14. Congenital Structural Defects of the Brain
15. Genetics of Neurodevelopmental Anomalies
16. Functional Effects of Drugs and Other Chemicals on the Developing Brain
17. Antenatal Screening for Neurologic Disorders
18. Antenatal Assessment of CNS Anomalies, including NTDs: Abdominal Ultrasound
19. Transvaginal Fetal Neuroscan
20. Epidemiology and Prevention of NTDs
SECTION IV Hemorrhagic and Ischemic Lesions
21. Fetal Cerebral Pathology of Hypoxic-Ischemic Origins
22. Multiple Pregnancy and Fetal Brain Injury
23. Infection, Inflammation and Brain Injury
24. Intracranial Hemorrhage
25. Ischemic Lesions of the Developing Brain
SECTION V Perinatal Asphyxia
26. Pathophysiology of Asphyxia
27. Antenatal Prediction of Asphyxia
28. Intrapartum Monitoring forAsphyxia
29. Prediction of Asphyxia with Fetal Blood Gas Analysis
30. The Asphyxiated Newborn Infant
31. Neuroprotection of the Fetal and Neonatal Brain
32. Medico-legal Issues: The UK Perspective
33. Medico-legal Issues: The US Perspective
SECTION VI Infection of the CNS
34. Toxoplasmosis
35. Viral Infections
36. Bacterial and Fungal Infections
SECTION VII Metabolic Disorders
37. Prenatal Diagnosis of Inborn Errors of Metabolism
38. Inborn Errors of Metabolism, Postnatal Diagnosis and Management
39. Degenerative Disorders of the Infant CNS
SECTION VIII Seizure Disorders
40. Seizure Disorders of the Neonate and Infant
SECTION IX the Special Senses
41. Disorders of Vision
42. Disorders of Hearing
SECTION X Disorders of the Nerve and Muscle
43. Disorders of the Spinal Cord, Cranial and Peripheral Nerves
44. Neuromuscular Disorders
SECTION XI Hydrocephalus and Neurosurgery
45. Fetal Neurosurgical Interventions
46. Neonatal Hydrocephalus - Clinical Assessment and Non-Surgical Management
47. Neurosurgical Management of Hydrocephalus
48. Neurosurgical Management of NTD
49. Congenital Defects, Vascular Malformations and Other Lesions
SECTION XII Epidemiology of Neurologic Disability
50. Epidemiology of Cerebral Palsy
51. Epidemiology of Mental Retardation
SECTION XIII Ethical Dilemmas
52. Issues for the Obstetrician
53. Issues for the Neonatologist
Ofertas